The Serum Cortisol test measures the level of cortisol, the body’s primary stress hormone, produced by the adrenal glands. It helps evaluate adrenal gland function and conditions of excess or deficient cortisol production.
Why is the Serum Cortisol done?
Ordered to investigate symptoms suggestive of excess cortisol (weight gain, high blood pressure, stretch marks) or deficiency (fatigue, weight loss, low blood pressure), and to evaluate adrenal gland function.
It can help your doctor assess
Cushing’s syndrome, Addison’s disease, and other adrenal gland or pituitary disorders affecting cortisol production.
Who may need this test?
This test may be considered for:
Anyone with symptoms suggestive of Cushing’s syndrome (excess cortisol) or Addison’s disease (cortisol deficiency)
People being evaluated for adrenal gland disorders.
Whether this test is right for you depends on your symptoms, medical history and the reason for testing - your doctor can advise.
What does this test measure?
The concentration of cortisol in the blood at a specific time of day (cortisol naturally follows a daily rhythm, highest in the morning).
Cortisol
Adrenal Hormone
Follows a daily rhythm - highest in the morning, lowest at night - so the timing of the sample matters for interpretation.
Understanding your Serum Cortisol results
How to read your result
Your report should be read using the reference interval, unit and method shown by the performing laboratory. A result outside a reference interval does not automatically establish a diagnosis, and a result inside the interval does not rule out every health problem. Clinical interpretation depends on symptoms, history and other findings.
Marker
Result
What it may be associated with
Cortisol
High
May indicate Cushing’s syndrome or significant physical/emotional stress at the time of testing.
Cortisol
Low
May indicate adrenal insufficiency (Addison’s disease) or pituitary gland problems affecting cortisol regulation.
If a result is outside the range
If the Serum Cortisol is reported as high, low, positive, negative or otherwise outside the laboratory's stated interval, the meaning depends on the specific test and the reason it was ordered. Your clinician may consider repeat testing, related investigations or other clinical information before deciding what the result means.
Limitations of this test
A single cortisol reading is influenced by many factors - doctors often use dynamic tests (like a suppression or stimulation test) for a more definitive diagnosis of adrenal disorders.
An abnormal result does not by itself mean you have a particular disease. Your doctor interprets results together with your symptoms, history and other tests.
Serum Cortisol normal range
Parameter
Reference range
Unit
Cortisol (morning, 8am)
5 - 25
µg/dL
Typical adult ranges for guidance. Reference intervals vary with the laboratory method, age and sex - always read your result against the range printed on your own report.
How should I prepare for the Serum Cortisol?
No fasting is needed - you can eat and drink normally.
Morning sample (8-9 AM) preferred.
Drink water as usual - being well hydrated makes the blood draw easier.
Tell the collection team about any medicines and supplements you take.
Do not stop prescribed medicines unless your doctor tells you to.
Follow any additional instructions our team shares when you book.
How sample collection works
01
Book
Choose the test and a time slot online, or call us and we'll book it for you.
02
Prepare
Follow the preparation steps above for this test.
03
Sample collection
A trained phlebotomist collects the sample at your home - no extra charge.
04
Laboratory processing
Your sample is processed in our laboratory and reviewed by a pathologist.
05
Report
Your report is shared on WhatsApp and email, usually within 24 hours.
For a blood-based test, a small blood sample is collected by a trained healthcare professional, usually from a vein in the arm. The collection normally takes only a few minutes; mild temporary discomfort or bruising can occur at the puncture site.
What can affect the result?
Time of day, recent stress, illness, and certain medicines (especially steroids) all significantly affect cortisol levels.
When should you talk to a doctor?
Laboratory results are interpreted together with your symptoms, medical history and other investigations. If your results are significantly abnormal, or you have symptoms that worry you, discuss them with a qualified doctor promptly.
Test details
Test name
Serum Cortisol
Test code
HWP-T0052
Department
Clinical Biochemistry
Sample type
Venous blood (from a vein in the arm)
Fasting
Not required
Report time
24 hours (next day)
Home collection
Available across Malad, Kandivali, Borivali & Goregaon
Price
₹899 (MRP ₹1,449, 38% off)
Availability
All days - lab open 24×7
References
Trusted public health sources for the information on this page:
1.Cortisol Test - MedlinePlus (US National Library of Medicine)
This information is for general awareness and does not replace advice from your doctor.
₹899₹1,44938% off
Serum Cortisol test price in Mumbai
The Serum Cortisol test cost in Mumbai at HWP Diagnostic is ₹899 - 38% less than the MRP of ₹1,449. There are no extra charges for home sample collection. The same price applies across Malad, Kandivali, Borivali and Goregaon.
Book the Serum Cortisol test with free home sample collection anywhere in Malad, Kandivali, Borivali and Goregaon, or walk in to our lab in Malad West, Mumbai - open 24×7.
Cortisol naturally follows a daily rhythm - highest around 8am and lowest at night - so your doctor will specify the timing needed for an accurate, interpretable result.
Do I need to fast for this test?
Fasting requirements vary - follow your doctor’s specific instructions, as timing matters more than fasting for this test.
Can stress affect my cortisol level at the time of testing?
Yes, acute stress can temporarily raise cortisol, which is one reason a single abnormal result is often followed up with additional, more specific testing.
What is the Serum Cortisol?
Serum Cortisol is a blood test. Measures the stress hormone cortisol - used to assess adrenal function.
Why is the Serum Cortisol done?
The Serum Cortisol may be ordered when a healthcare professional needs information about the condition or health area assessed by this test. Cortisol is the body's main stress hormone, following a natural daily rhythm. Measuring it helps assess adrenal gland function and conditions linked to too much or too little cortisol.
What does the Serum Cortisol test measure?
Measures the stress hormone cortisol - used to assess adrenal function.
Who may need the Serum Cortisol?
The test may be relevant for people whose symptoms, medical history, screening needs or treatment monitoring match the purpose of the Serum Cortisol.
How should I prepare for the Serum Cortisol?
Morning sample (8-9 AM) preferred.
Do I need to fast for the Serum Cortisol?
No, fasting is not required for the Serum Cortisol. You can eat and drink normally unless your doctor has advised otherwise.
What sample is required for the Serum Cortisol?
The Serum Cortisol is done on a blood sample.
How is the Serum Cortisol sample collected?
For a blood-based test, a small blood sample is collected by a trained healthcare professional, usually from a vein in the arm. The collection normally takes only a few minutes; mild temporary discomfort or bruising can occur at the puncture site.
How long does the Serum Cortisol take to report?
Reports for the Serum Cortisol are usually ready within 24 hours of sample collection. You receive them on WhatsApp and email.
What is the price of the Serum Cortisol?
The Serum Cortisol costs Rs 549 at HWP Diagnostic (MRP Rs 900). Home sample collection is free.
How do I understand my Serum Cortisol result?
Your report should be read using the reference interval, unit and method shown by the performing laboratory. A result outside a reference interval does not automatically establish a diagnosis, and a result inside the interval does not rule out every health problem. Clinical interpretation depends on symptoms, history and other findings.
What does a high or low Serum Cortisol result mean?
If the Serum Cortisol is reported as high, low, positive, negative or otherwise outside the laboratory's stated interval, the meaning depends on the specific test and the reason it was ordered. Your clinician may consider repeat testing, related investigations or other clinical information before deciding what the result means.
Can a Serum Cortisol diagnose a disease by itself?
The Serum Cortisol can provide important information, but laboratory results are generally interpreted together with symptoms, medical history, examination and other investigations. A single result should not be treated as a diagnosis without clinical context.
Can medicines affect the Serum Cortisol result?
Some medicines, supplements, food, exercise and other pre-test factors can affect particular laboratory results. Tell the healthcare professional about medicines and supplements you take, and do not stop prescribed medicines unless your clinician tells you to.
Is the Serum Cortisol available for home collection?
Yes. Free home sample collection for the Serum Cortisol is available across Malad, Kandivali, Borivali and Goregaon in Mumbai. You can also visit our Malad West lab, open 24x7.
What is the Serum Cortisol test?Why is the Serum Cortisol test done?